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Sunday, June 1, 2008

Men No Longer Needed to Create Sperm

Scientists at the University of Newcastle have managed to create human sperm cells using a female embryonic stem cell.

The researchers, led by Prof Karim Nayernia, had previously created primitive sperm cells from male bone marrow. They’re currently working on making the cells from female bone marrow, which would be much easier and more practical than creating them from embryos.

The creation means that lesbian couples could soon have children that shared the DNA of both women, rather than having one male biological father. A sperm cell created from one partner could fertilize her partner’s egg.

There is some question about whether a sperm cell created from a female could produce viable, healthy offspring. The human female sperm cells could not in their current state produce offspring as they do not have the correct amount of genetic material. The team must next have the cells undergo meiosis to make sure the cells have the correct amount of genetic material.

That will likely only be a minor roadblock. Prof Nayernia has already overcome this problem with sperm cells created from male cells. In 2006, he used sperm created from embryonic stem cells to impregnate mice. The mice produced 7 pups, although one died and the other six had health problems.

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