Why Terri Hatcher is so stupid: Explained.

April 1 (Bloomberg) -- Botulinum neurotoxin type A, sold as Allergan Inc.'s Botox remedy for wrinkles, can move from its injection site to the brain, a study shows.

Scientists injected rats' whisker muscles with botulism toxin. Tests of the rodents' brain tissue found that botulism had been transported to the brain stems, the researchers said in the Journal of Neuroscience published April 2.

``The idea that there could be some transmission of this [botulism] to the central nervous system needs to be followed up,'' said Mathew Avram, the director of Massachusetts General Hospital's Dermatology, Laser and Cosmetic Center, in Boston, in a telephone interview today. ``But this treatment has been used on millions of people for years, and we're not seeing major central nervous system uses with it.''

Botulism neurotoxin can disrupt nerve cells' ability to communicate and may change spinal cord circuitry, the authors wrote in the study.

Mouse and rat physiology is different from that of humans, so the results may not predict what happens in people, Avram said. He wasn't involved in the study.
The study isn't conclusive, and because it contradicts previous findings, more work is necessary, according to an Allergan spokeswoman. The company is based in Irvine, California.

``We are aware from monkey studies already published that toxin A[test toxin] migrates more than B[real botox],'' Salazar said. ``Monkeys are more like humans than rodents, so these findings we're observing are consistent.''

still. creepy.